" /> APOA1 wt Allele - CISMeF





Preferred Label : APOA1 wt Allele;

NCIt synonyms : Apolipoprotein A-I Gene; Apolipoprotein A1 wt Allele; Apolipoprotein of High Denisity Lipoprotein Gene;

NCIt definition : Human APOA1 wild-type allele is located within 11q23-q24 and is approximately 2 kb in length. This allele, which encodes apolipoprotein A-I protein, plays a role in cholesterol metabolism and transport. Mutation of the gene is associated with several types of amyloidosis, APOA1 deficiency, hypoalphalipoproteinemia, autosomal recessive corneal clouding, and high density lipoprotein deficiency types 1 (recessive) and 2 (autosomal dominant). Fusion of this gene with the neighboring APOC3 gene is associated with combined apoA-I and apoC-III deficiency.;

GenBank Accession Number : X02162;

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12/05/2024


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