apolipoprotein A-I

Preferred Label : apolipoprotein A-I;

MeSH definition : The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus promoting efflux of cholesterol to HDL then to the LIVER for excretion from the body (reverse cholesterol transport). It also acts as a cofactor for LECITHIN CHOLESTEROL ACYLTRANSFERASE that forms CHOLESTEROL ESTERS on the HDL particles. Mutations of this gene APOA1 cause HDL deficiency, such as in FAMILIAL ALPHA LIPOPROTEIN DEFICIENCY DISEASE and in some patients with TANGIER DISEASE.;

MeSH synonym : apoa-1; apo a-i; apolipoprotein ai; apo a1; apolipoprotein a 1; apoa-i; apolipoprotein a-1; apolipoprotein a1; apo a-1; apo ai; apolipoprotein A I;

MeSH hyponym : apolipoprotein A-I isoproteins; apolipoprotein A-I Isoprotein-4; Pro-Apolipoprotein A-I; apolipoprotein A-I Isoprotein-2; Pro Apolipoprotein A I; Pro-Apo A-I; Pro Apo A I; Proapolipoprotein AI; Apolipoprotein AI Propeptide; Apolipoprotein A I Isoproteins; Apo A-I Isoproteins; Apo A I Isoproteins; Apolipoprotein A I Isoprotein 2; Apolipoprotein A I Isoprotein 4;

Is substance : O;

Details

Origin ID

D016632;

UMLS CUI

C0085201;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Apolipoprotein A-I [LOINC component]
- Apolipoprotein A-I [MedDRA Preferred Term]
- Apolipoprotein A-I (substance) [SNOMED CT concept]
- Apolipoprotein a-I [OMIM gene]
- apolipoprotein A1 [ORDO Gene]
- apolipoprotein a-i [SNOMED Notion]
Indexing information
- AP-4F peptide [MeSH Supplementary Concept]
- L-4F peptide [MeSH Supplementary Concept]
Record concept(s)
- Pro-Apolipoprotein A-I [MeSH concept]
- apolipoprotein A-I [MeSH concept]
- apolipoprotein A-I Isoprotein-2 [MeSH concept]
- apolipoprotein A-I Isoprotein-4 [MeSH concept]
- apolipoprotein A-I isoproteins [MeSH concept]
Related MeSH Supplementary Concept(s)
- APOA1 protein, human [MeSH Supplementary Concept]
- Apoa1 protein, mouse [MeSH Supplementary Concept]
- CER-001 [MeSH Supplementary Concept]
- D-4F peptide [MeSH Supplementary Concept]
- ETC216 [MeSH Supplementary Concept]
- MDCO-216 [MeSH Supplementary Concept]
- apolipoprotein A-I baltimore [MeSH Supplementary Concept]
- apolipoprotein A-I giessen [MeSH Supplementary Concept]
- apolipoprotein A-I helsinki [MeSH Supplementary Concept]
- apolipoprotein A-I milano [MeSH Supplementary Concept]
- apolipoprotein A-I paris [MeSH Supplementary Concept]
- apolipoprotein A-I tangier [MeSH Supplementary Concept]
- apolipoprotein A-I zaragoza [MeSH Supplementary Concept]
- apolipoprotein A-I zavalla [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Apolipoprotein A-I [LOINC part]
- Apolipoprotein A-I [LOINC component]
- Apolipoprotein A-I (substance) [SNOMED CT concept]
- apolipoprotein a-i [SNOMED Notion]

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