Preferred Label : apolipoprotein A-I;

MeSH definition : The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus promoting efflux of cholesterol to HDL then to the LIVER for excretion from the body (reverse cholesterol transport). It also acts as a cofactor for LECITHIN CHOLESTEROL ACYLTRANSFERASE that forms CHOLESTEROL ESTERS on the HDL particles. Mutations of this gene APOA1 cause HDL deficiency, such as in FAMILIAL ALPHA LIPOPROTEIN DEFICIENCY DISEASE and in some patients with TANGIER DISEASE.;

MeSH synonym : apoa-1; apo a-i; apolipoprotein ai; apo a1; apolipoprotein a 1; apoa-i; apolipoprotein a-1; apolipoprotein a1; apo a-1; apo ai; apolipoprotein A I;

MeSH hyponym : apolipoprotein A-I isoproteins; apolipoprotein A-I Isoprotein-4; Pro-Apolipoprotein A-I; apolipoprotein A-I Isoprotein-2; Pro Apolipoprotein A I; Pro-Apo A-I; Pro Apo A I; Proapolipoprotein AI; Apolipoprotein AI Propeptide; Apolipoprotein A I Isoproteins; Apo A-I Isoproteins; Apo A I Isoproteins; Apolipoprotein A I Isoprotein 2; Apolipoprotein A I Isoprotein 4;

Is substance : O;

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The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus promoting efflux of cholesterol to HDL then to the LIVER for excretion from the body (reverse cholesterol transport). It also acts as a cofactor for LECITHIN CHOLESTEROL ACYLTRANSFERASE that forms CHOLESTEROL ESTERS on the HDL particles. Mutations of this gene APOA1 cause HDL deficiency, such as in FAMILIAL ALPHA LIPOPROTEIN DEFICIENCY DISEASE and in some patients with TANGIER DISEASE.

http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=93560
2011
France
scientific and technical information
amyloidosis
amyloid
apolipoprotein A-I
amyloidosis, nos
amyloidosis
amylose
apolipoproteins a
amyloidosis, familial visceral

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http://www.has-sante.fr/portail/jcms/c_815979/exploration-dune-dyslipidemie-quelle-place-pour-le-dosage-des-apolipoproteines-a1-et-b
http://www.has-sante.fr/portail/jcms/c_808407/fiche-bon-usage-des-technologies-de-sante-dosages-des-apolipoproteines-a1-et-b
2009
France
French
diagnostic uses of chemicals
dyslipidemias
apolipoprotein A-I
apolipoprotein a-ii
guidelines for medical devices use

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27/07/2025


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