Bcl-2-Associated Transcription Factor 1

Preferred Label : Bcl-2-Associated Transcription Factor 1;

NCIt synonyms : BCL2-Associated Transcription Factor 1; Btf; BCLAF1;

NCIt definition : Bcl-2-associated transcription factor 1 (920 aa, 106 kDa) is encoded by the human BCLAF1 gene. This protein is involved in the positive regulation of apoptosis and the negative regulation of gene transcription.;

NCIt note : There are 4 known isoforms of the Bcl-2-associated transcription factor 1 protein produced by alternative splicing of the BCLAF1 gene. (UniProt);

NCI Metathesaurus CUI : CL473362;

Details

Origin ID

C115996;

UMLS CUI

C1431883;

Automatic exact mappings (from CISMeF team)
- Bcl2-associated transcription factor 1 [OMIM gene]
OMIM relation
- Bcl2-associated transcription factor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- BCLAF1 protein, human [MeSH Supplementary Concept]
- BCLAF1 protein, human [MeSH concept]
gene_encodes_gene_product
- BCLAF1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Transcription Repressor/Corepressor [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Positive Regulation of Apoptosis [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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