Msx2-Interacting Protein

Preferred Label : Msx2-Interacting Protein;

NCIt synonyms : SMART/HDAC1 Associated Repressor Protein; Nuclear Receptor Transcription Cofactor; SMART/HDAC1-Associated Repressor Protein; Msx2 Interacting Nuclear Target; SPEN Homolog; SPEN;

NCIt definition : Msx2-interacting protein (3664 aa, 402 kDa) is encoded by the human SPEN gene. This protein plays a role in the negative regulation of gene transcription.;

Details

Origin ID

C115312;

UMLS CUI

C1310944;

Automatic exact mappings (from CISMeF team)
- Spen family transcriptional repressor [OMIM gene]
- solid and papillary epithelial neoplasm [Radlex concept]
- spen family transcriptional repressor [ORDO Gene]
OMIM relation
- Spen family transcriptional repressor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SPEN protein, human [MeSH Supplementary Concept]
- SPEN protein, human [MeSH concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- SPEN Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_structural_domain_or_motif
- RNA Recognition Motif [NCIt concept]
gene_product_plays_role_in_biological_process
- Neural Development [NCIt concept]
- Signal Transduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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