Trefoil Factor 2

Preferred Label : Trefoil Factor 2;

NCIt synonyms : Spasmolytic Polypeptide; Spasmolysin; SP; Spasmolytic Protein 1; TFF2;

NCIt definition : Trefoil factor 2 (129 aa, 14 kDa) is encoded by the human TFF2 gene. This protein is involved in the negative regulation of gastrointestinal motility and gastric acid secretion.;

Details

Origin ID

C115190;

UMLS CUI

C0905072;

Automatic exact mappings (from CISMeF team)
- Status post (contextual qualifier) (qualifier value) [SNOMED CT concept]
- Trefoil factor 2 [OMIM gene]
- cortical subplate [UBERON concept]
- proxyphylline [MeSH Supplementary Concept]
- spasmolysin [MeSH concept]
- spasmolytic polypeptide [MeSH Supplementary Concept]
- spasmolytic polypeptide [MeSH concept]
- trefoil factor 2 [HGNC gene]
Currated CISMeF NLP mapping
- Trefoil Factor-2 [MeSH Descriptor]
- Trefoil Factor-2 [MeSH concept]
OMIM relation
- Trefoil factor 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TFF2 protein, human [MeSH Supplementary Concept]
- TFF2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- TFF2 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_chemical_classification
- Trefoil Family [NCIt concept]
gene_product_has_structural_domain_or_motif
- Trefoil Motif [NCIt concept]
gene_product_plays_role_in_biological_process
- Digestion [NCIt concept]
- Gastric Acid Secretion Inhibition [NCIt concept]

Keyword's position in hierarchy(ies) :

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