Transducin-Like Enhancer Protein 2

Preferred Label : Transducin-Like Enhancer Protein 2;

NCIt synonyms : Enhancer of Split Groucho-Like Protein 2; Transducin-Like Enhancer of Split 2; Enhancer of Split Groucho 2; ESG2; TLE2;

NCIt definition : Transducin-like enhancer protein 2 (743 aa, 80 kDa) is encoded by the human TLE2 gene. This protein is involved in Notch and Wnt signaling pathways and transcriptional repression.;

Details

Origin ID

C115082;

UMLS CUI

C1431649;

Automatic exact mappings (from CISMeF team)
- TLE family member 2, transcriptional corepressor [HGNC gene]
- Tle family member 2, transcriptional corepressor [OMIM gene]
OMIM relation
- Tle family member 2, transcriptional corepressor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TLE2 protein, human [MeSH Supplementary Concept]
- TLE2 protein, human [MeSH concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- TLE2 Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Transcription Repressor/Corepressor [NCIt concept]
gene_product_has_structural_domain_or_motif
- WD Repeat [NCIt concept]
gene_product_plays_role_in_biological_process
- Organogenesis [NCIt concept]
- Signal Transduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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