Gamma-Interferon-Inducible Protein 16

Preferred Label : Gamma-Interferon-Inducible Protein 16;

NCIt synonyms : Interferon-Inducible Myeloid Differentiation Transcriptional Activator; IFI 16; Interferon-Gamma Induced Protein; Interferon-Gamma-Inducible Protein 16; Ifi-16; IFI16;

NCIt definition : Gamma-interferon-inducible protein 16 (785 aa, 88 kDa) is encoded by the human IFI16 gene. This protein plays a role in both immune response-mediated programmed cell death and transcriptional regulation.;

NCIt note : Acetylation of the nuclear localization signal found in gamma-interferon-inducible protein 16 promotes retention of the protein in the cytoplasm. (UniProt);

Details

Origin ID

C115028;

UMLS CUI

C1447180;

Automatic exact mappings (from CISMeF team)
- Interferon-gamma-inducible protein 16 [OMIM gene]
OMIM relation
- Interferon-gamma-inducible protein 16 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- IFI16 protein, human [MeSH Supplementary Concept]
- IFI16 protein, human [MeSH concept]
gene_encodes_gene_product
- IFI16 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Transcription Repressor/Corepressor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Nuclear Localization Signal [NCIt concept]
gene_product_plays_role_in_biological_process
- Antiviral Response [NCIt concept]
- Autophagy [NCIt concept]
- DNA Binding [NCIt concept]
- Immune Response Process [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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