Viral Interleukin-6 Homolog

Preferred Label : Viral Interleukin-6 Homolog;

NCIt synonyms : Interleukin-6 Homolog; Putative Interleukin 6; vIL-6; Viral Interleukin-6; ORF K2; K2;

NCIt definition : Viral interleukin-6 homolog (204 aa, 23 kDa) is encoded by the human herpesvirus 8 K2 gene. This protein is involved in the negative regulation of apoptosis and the positive regulation of both cell proliferation and cell differentiation.;

Details

Origin ID

C114503;

UMLS CUI

C3889727;

Automatic exact mappings (from CISMeF team)
- Keratin 2, type II [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- HHV8 K2 Gene [NCIt concept]
- Viral Gene [NCIt concept]
gene_product_has_organism_source
- Virus [NCIt concept]
gene_product_plays_role_in_biological_process
- Immunologic Tolerance [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Positive Regulation of Cell Differentiation [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]

Keyword's position in hierarchy(ies) :

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