RNA-Binding Motif, Single-Stranded-Interacting Protein 1

Preferred Label : RNA-Binding Motif, Single-Stranded-Interacting Protein 1;

NCIt synonyms : Suppressor of CDC2 With RNA-Binding Motif 2; c-Myc Gene Single Strand Binding Protein 2; Single-Stranded DNA-Binding Protein MSSP-1;

NCIt definition : RNA-binding motif, single-stranded-interacting protein 1 (406 aa, 45 kDa) is encoded by the human RBMS1 gene. This protein is involved in both single-stranded DNA binding and DNA replication.;

NCIt note : RNA-binding motif, single-stranded-interacting protein 1 binds to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. This sequence is found in the 5' untranslated region of the human MYC gene, where it serves as both an origin of replication and as a transcriptional enhancer. (UniProt and OMIM);

Details

Origin ID

C114447;

UMLS CUI

C0252967;

Automatic exact mappings (from CISMeF team)
- RNA binding motif single stranded interacting protein 1 [HGNC gene]
OMIM relation
- Rna-binding motif protein, single strand-interacting, 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- RBMS1 protein, human [MeSH Supplementary Concept]
- RBMS1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- RBMS1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- RNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- RNA Recognition Motif [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- DNA Replication [NCIt concept]
- RNA Binding [NCIt concept]
- RNA Processing [NCIt concept]

Keyword's position in hierarchy(ies) :

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