NRXN3 wt Allele

Preferred Label : NRXN3 wt Allele;

NCIt synonyms : Chromosome 14 Open Reading Frame 60 Gene; C14orf60; Neurexin 3 wt Allele; KIAA0743;

NCIt definition : Human NRXN3 wild-type allele is located in the vicinity of 14q31 and is approximately 1622 kb in length. This allele, which encodes neurexin-3 protein, plays a role in cell adhesion and cell recognition. Genetic variations at this locus have been associated with alcohol dependence and autism spectrum disorder.;

NCIt note : Alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms. Transcripts that initiate from an upstream promoter encode alpha isoforms while transcripts initiating from the downstream promoter encode beta isoforms.;

GenBank Accession Number : NM_001105250;

Details

Origin ID

C113538;

UMLS CUI

C3814862;

OMIM relation
- Neurexin III [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 14q31 [NCIt concept]
gene_is_element_in_pathway
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Synaptic Junction Pathway [NCIt concept]
gene_plays_role_in_process
- Angiogenic Process [NCIt concept]
- Cell Adhesion Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Neural Development [NCIt concept]
- Neurologic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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