Absence of Biallelic TCRgamma Deletion

Preferred Label : Absence of Biallelic TCRgamma Deletion;

NCIt synonyms : Absence of Biallelic TCRgamma Locus Deletion; ABD;

NCIt definition : The absence of rearrangement of at least one allele of the T-cell receptor gamma gene locus. This lack of rearrangement is characteristic of early thymocyte precursors and a lack of V(D)J recombination. This genetic profile is a predictor of induction therapy failure in children with T-cell acute lymphoblastic leukemia.;

PubMed : 20644084;

Détails

Origin ID

C113506;

UMLS CUI

C3811055;

Automatic exact mappings (from CISMeF team)
- ABD (body structure) [SNOMED CT concept]
Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
cytogenetic_abnormality_involves_chromosome
- Human Chromosome 7 [NCIt concept]
molecular_abnormality_involves_gene
- T-Cell Receptor Gamma Locus [NCIt concept]
- T-Cell Receptor Gene [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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