Absence of Biallelic TCRgamma DeletionNCIt concept
Preferred Label : Absence of Biallelic TCRgamma Deletion;
NCIt synonyms : Absence of Biallelic TCRgamma Locus Deletion; ABD;
NCIt definition : The absence of rearrangement of at least one allele of the T-cell receptor gamma gene
locus. This lack of rearrangement is characteristic of early thymocyte precursors
and a lack of V(D)J recombination. This genetic profile is a predictor of induction
therapy failure in children with T-cell acute lymphoblastic leukemia.;