NCIt related terms : ACTH Producing Pituitary Adenoma;
NCIt definition : Cushing's syndrome due to abnormally high secretion of adrenocorticotropic hormone
(ACTH) from the pituitary gland.;
Alternative definition : NICHD: Cushing syndrome due to an adrenocorticotropic hormone-producing adenoma in
the pituitary gland.; NCI-GLOSS: A condition in which there is too much cortisol (a hormone made by the
outer layer of the adrenal gland) in the body. In Cushing disease, this happens when
an adenoma (benign tumor) in the pituitary gland makes too much adrenocorticotropic
hormone (ACTH). This causes the adrenal gland to make too much cortisol. Symptoms
include a round face, thin arms and legs, severe fatigue and muscle weakness, high
blood pressure and high blood sugar, purple or pink stretch marks on the skin, and
weight gain, especially in the abdomen.;