Transmembrane Glycoprotein NMB

Preferred Label : Transmembrane Glycoprotein NMB;

NCIt synonyms : Transmembrane Glycoprotein HGFIN; gpNMB; Glycoprotein Nmb-Like Protein; Glycoprotein Nonmetastatic B; Glycoprotein NMB; Osteoactivin;

NCIt definition : Transmembrane glycoprotein NMB (572 aa, 64 kDa) is encoded by the human GPNMB gene. This protein may play a role in cell proliferation.;

NCIt note : Transmembrane glycoprotein NMB is the target for Glembatumumab Vedotin.;

Details

Origin ID

C113116;

UMLS CUI

C3813203;

Automatic exact mappings (from CISMeF team)
- Glycoprotein nmb [OMIM gene]
- Glycoproteins [LOINC component]
- glycoprotein nmb [ORDO Gene]
- glycoprotein nmb [HGNC gene]
- glycoproteins [MeSH Descriptor]
OMIM relation
- Glycoprotein nmb [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- GPNMB Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Inhibition of Cell Proliferation [NCIt concept]
is_target
- Glembatumumab Vedotin [NCIt concept]

Keyword's position in hierarchy(ies) :

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