Transcription Factor SOX-4

Preferred Label : Transcription Factor SOX-4;

NCIt synonyms : SOX-4; SOX4;

NCIt definition : Transcription factor SOX-4 (474 aa, 47 kDa) is encoded by the human SOX4 gene. This protein plays a role in both T-cell differentiation and transcriptional activation.;

NCIt note : Transcription factor SOX-4 binds with high affinity to the T-cell enhancer sequence 5'-AACAAAG-3' . (UniProt);

Details

Origin ID

C112921;

UMLS CUI

C3813222;

Automatic exact mappings (from CISMeF team)
- SOX4 transcription factor [MeSH concept]
- SOXC transcription factors [MeSH Descriptor]
- SRY-box transcription factor 4 [ORDO Gene]
- Sry-box 4 [OMIM gene]
OMIM relation
- Sry-box 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- SOX4 Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
- Transcription Coactivator [NCIt concept]
gene_product_has_structural_domain_or_motif
- HMG-Box [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Morphogenesis [NCIt concept]
- T-Cell Differentiation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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