NCIt synonyms : Makorin Ring Finger Protein 1 wt Allele; RING Finger Protein 61 Gene; RNF61;
NCIt definition : Human MKRN1 wild-type allele is located in the vicinity of 7q34 and is approximately
27 kb in length. This allele, which encodes E3 ubiquitin-protein ligase makorin-1
protein, plays a role in post-translational protein ubiquitination. A fusion of this
gene and the BRAF gene may be associated with pilocytic astrocytoma.;