Chromatin Assembly Factor I

Preferred Label : Chromatin Assembly Factor I;

NCIt synonyms : CAF-1; Chromatin Assembly Factor 1 Complex; CAF-1 Complex; Chromatin Assembly Factor 1; CAF-I; Chromatin Assembly Factor I Complex; CAF1;

NCIt definition : A heterotrimeric protein complex that mediates chromatin assembly by promoting histone H3 and H4 deposition onto newly synthesized DNA during replication or DNA repair. This complex is comprised of chromatin assembly factor 1 subunit A, chromatin assembly factor 1 subunit B and histone-binding protein RBBP4.;

Details

Origin ID

C111912;

UMLS CUI

C3853876;

Automatic exact mappings (from CISMeF team)
- CAF-1 complex [GO term]
- Ccr4-not transcription complex, subunit 7 [OMIM gene]
- chromatin assembly Factor-1 [MeSH concept]
- chromatin assembly Factor-1 [MeSH Descriptor]
- chromatin assembly factor 1 subunit B [HGNC gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_product_has_biochemical_function
- Chromatin Remodeling Factor [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Remodeling [NCIt concept]
has_gene_product_element
- Chromatin Assembly Factor 1 Subunit A [NCIt concept]
- Histone-Binding Protein RBBP4 [NCIt concept]

Keyword's position in hierarchy(ies) :

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