Keratin, Type I Cytoskeletal 18

Preferred Label : Keratin, Type I Cytoskeletal 18;

NCIt synonyms : CK-18; K18; Cytokeratin-18; Cell Proliferation-Inducing Gene 46 Protein; Keratin-18; Cytokeratin 18; Cell Proliferation-Inducing Protein 46; KRT18;

NCIt definition : Keratin, type I cytoskeletal 18 (430 aa, 48 kDa) is encoded by the human KRT18 gene. This protein plays a role in both intermediate filament structure and the inhibition of apoptosis.;

NCIt note : Keratin, type I cytoskeletal 18 is found in a heterotetramer comprised of 2 keratin, type I cytoskeletal 18 and 2 keratin, type II cytoskeletal 8. (UniProt);

Details

Origin ID

C111868;

UMLS CUI

C1455201;

Automatic exact mappings (from CISMeF team)
- CK18 [MedDRA LLT]
- Cytokeratin 18 [MedDRA Preferred Term]
- K-18 conjugate [MeSH Supplementary Concept]
- Keratin 18, type I [OMIM gene]
- Keratin-18 [MeSH Descriptor]
- Keratin-18 [MeSH concept]
OMIM relation
- Keratin 18, type I [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- KRT18 protein, human [MeSH Supplementary Concept]
- KRT18 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytoskeletal Gene [NCIt concept]
- Intermediate Filament Gene [NCIt concept]
- KRT18 Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoskeleton [NCIt concept]
- Intermediate Filament [NCIt concept]
- Keratin Filament [NCIt concept]
gene_product_has_biochemical_function
- Scaffolding Protein [NCIt concept]
gene_product_has_chemical_classification
- Cytokeratin [NCIt concept]
gene_product_is_element_in_pathway
- Pathogenic Escherichia coli Infection Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Movement Process [NCIt concept]
- Cytoskeletal Modeling [NCIt concept]
- Cytoskeletal Process [NCIt concept]
- Keratinization [NCIt concept]
- Membrane Protein Traffic [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Regulation of Cell Shape [NCIt concept]

Keyword's position in hierarchy(ies) :

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