" /> Selatinib Ditosilate - CISMeF





Preferred Label : Selatinib Ditosilate;

NCIt definition : An orally bioavailable ditosilate salt form of selatinib, an analog of the quinazoline lapatinib and dual inhibitor of epidermal growth factor receptor (EGFR) and Human Epidermal Growth Factor Receptor 2 (ErbB-2 or HER-2), with potential antineoplastic activity. Upon administration, selatinib reversibly blocks phosphorylation of both EGFR and ErbB2, thereby suppressing tumor growth in EGFR/ErbB-2-overexpressing tumor cells. The tyrosine kinases EGFR and ErbB2 have been implicated in the growth of various tumor types.;

UNII : 6Q2E32HVE7;

CAS number : 1452886-38-2;

NCI Metathesaurus CUI : CL454151;

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10/07/2025


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