BCR-ABL TKI-Resistant Mutation

Preferred Label : BCR-ABL TKI-Resistant Mutation;

NCIt synonyms : BCR-ABL Tyrosine Kinase Inhibitor-Resistant Mutation; BCR-ABL1 TKI-Resistant Mutation; BCR/ABL1 Tyrosine Kinase Inhibitor-Resistant Mutation; BCR/ABL TKI-Resistant Mutation; BCR-ABL1 Tyrosine Kinase Inhibitor-Resistant Mutation; BCR/ABL1 TKI-Resistant Mutation; BCR::ABL TKI-Resistant Mutation;

NCIt definition : A molecular genetic abnormality in the kinase domain of the BCR-ABL fusion gene that results in resistance to tyrosine kinase inhibitors.;

Details

Origin ID

C110963;

UMLS CUI

C3831388;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
is_abnormality_of_gene
- BCR/ABL1 Fusion Gene with ABL1 NM_005157.4:c.1075T>G Mutation [NCIt concept]
- BCR/ABL1 Fusion Gene with ABL1 NM_005157.4:c.763G>A Mutation [NCIt concept]
- BCR/ABL1 Fusion Gene with ABL1 NM_005157.4:c.764A>T Mutation [NCIt concept]
- BCR/ABL1 Fusion Gene with ABL1 NM_005157.4:c.895G>C Mutation [NCIt concept]
- BCR/ABL1 Fusion Gene with ABL1 NM_005157.4:c.895G>T Mutation [NCIt concept]
- BCR/ABL1 Fusion Gene with ABL1 NM_005157.4:c.944C>T Mutation [NCIt concept]
- BCR/ABL1 Fusion Gene with ABL1 NM_005157.4:c.949T>C Mutation [NCIt concept]
- BCR/ABL1 Fusion Gene with ABL1 NM_005157.4:c.951C>A Mutation [NCIt concept]
- BCR/ABL1 Fusion Gene with ABL1 NM_005157.4:c.951C>G Mutation [NCIt concept]
molecular_abnormality_involves_gene
- ABL1 Gene [NCIt concept]
- BCR Gene [NCIt concept]
- BCR/ABL1 Fusion Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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