GATOR Complex Protein NPRL3

Preferred Label : GATOR Complex Protein NPRL3;

NCIt synonyms : Protein CGTHBA; NPRL3; Alpha-Globin Regulatory Element-Containing Gene Protein; -14 Gene Protein; Nitrogen Permease Regulator 3-Like Protein;

NCIt definition : GATOR complex protein NPRL3 (569 aa, 64 kDa) is encoded by the human NPRL3 gene. This protein has no known function.;

NCIt note : DEPDC5, NPRL2 and NPRL3 are subunits of the GATOR1 (GAP Activity TOward Rags 1) complex, which inhibits the amino acid-sensing branch of the mTORC1 pathway.;

Details

Origin ID

C106288;

UMLS CUI

C3811759;

Automatic exact mappings (from CISMeF team)
- NPR3 like, GATOR1 complex subunit [ORDO Gene]
- Nitrogen permease regulator-like 3 [OMIM gene]
OMIM relation
- Nitrogen permease regulator-like 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- NPRL3 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Lysosome [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- mTOR Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Autophagy [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tumor Suppression [NCIt concept]

Keyword's position in hierarchy(ies) :

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