Transcription Factor HES-3

Preferred Label : Transcription Factor HES-3;

NCIt synonyms : Hairy and Enhancer of Split 3; Class B Basic Helix-Loop-Helix Protein 43; HES3; bHLHb43;

NCIt definition : Transcription factor HES-3 (186 aa, 20 kDa) is encoded by the human HES3 gene. This protein plays a role in the repression of transcription.;

NCIt note : Transcription factor HES-3 binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG). (UniProt);

Details

Origin ID

C104532;

UMLS CUI

C3537290;

OMIM relation
- Hes family bhlh transcription factor 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- HES3 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
- Transcription Repressor/Corepressor [NCIt concept]
gene_product_has_chemical_classification
- BHLH Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- bHLH Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Nervous System Development [NCIt concept]
- Neural Development [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients