Erdafitinib - CISMeF

Preferred Label : Erdafitinib;

NCIt synonyms : 1,2-Ethanediamine, N1-(3,5-dimethoxyphenyl)-N2-(1-methylethyl)-N1-(3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl)-;

NCIt definition : An orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. Upon oral administration, erdafitinib binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways and thus the inhibition of tumor cell proliferation and tumor cell death in FGFR-overexpressing tumor cells. FGFR, upregulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cell proliferation, differentiation and survival.;

UNII : 890E37NHMV;

InChIKey : OLAHOMJCDNXHFI-UHFFFAOYSA-N;

CAS number : 1346242-81-6;

Drug name : Balversa;

Molecule name : JNJ-42756493; JNJ 42756493;

Codes from synonyms : 196;

Details

Origin ID

C103273;

UMLS CUI

C4519323;

Currated CISMeF NLP mapping
- Erdafitinib [SMS substance]
- Erdafitinib (substance) [SNOMED CT concept]
- erdafitinib [MeSH concept]
- erdafitinib [MeSH Supplementary Concept]
Manual BTNT mappings - CISMeF
- erdafitinib [ATC Code]
See also inter- (CISMeF)
- Product containing erdafitinib (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Erdafitinib (substance) [SNOMED CT concept]
- Product containing erdafitinib (medicinal product) [SNOMED CT concept]
- erdafitinib [MeSH Supplementary Concept]
- erdafitinib [ATC Code]
Validated automatic mappings to BTNT
- Balversa [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Fibroblast Growth Factor Receptor Family [NCIt concept]
is_component_of_chemotherapy_regimen
- Erdafitinib Regimen [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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