Homeobox Protein OTX2

Preferred Label : Homeobox Protein OTX2;

NCIt synonyms : Orthodenticle Homolog 2;

NCIt definition : Homeobox protein OTX2 (289 aa, 32 kDa) is encoded by the human OTX2 gene. This protein is involved in both transcriptional regulation and embryonic development.;

NCIt note : Homeobox protein OTX2 can bind to the bicoid target sequence (BTS): 5'-TCTAATCCC-3'. (UniProt);

Détails

Origin ID

C102953;

UMLS CUI

C1528381;

Automatic exact mappings (from CISMeF team)
- otx transcription factors [MeSH Descriptor]
OMIM relation
- Orthodenticle homeobox 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- OTX2 protein, human [MeSH Supplementary Concept]
- OTX2 protein, human [MeSH concept]
- Otx2 transcription factor [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- OTX2 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Brain [NCIt concept]
- Embryo [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Homeobox Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Homeo Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Embryogenesis [NCIt concept]
- Neural Development [NCIt concept]
- Signal Transduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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