SAM Pointed Domain-Containing Ets Transcription Factor

Preferred Label : SAM Pointed Domain-Containing Ets Transcription Factor;

NCIt synonyms : Prostate-Specific Ets; Prostate Epithelium-Specific Ets Transcription Factor; Prostate-Derived Ets Factor; SPDEF;

NCIt definition : SAM pointed domain-containing Ets transcription factor (335 aa, 38 kDa) is encoded by the human SPDEF gene. This protein is involved in transcriptional regulation and may modulate both prostate development and prostate cancer progression.;

NCIt note : SAM pointed domain-containing Ets transcription factor binds to 5'-GGAT-3' DNA sequences. (UniProt);

Details

Origin ID

C102920;

UMLS CUI

C3537378;

Automatic exact mappings (from CISMeF team)
- Sam pointed domain-containing ets transcription factor [OMIM gene]
OMIM relation
- Sam pointed domain-containing ets transcription factor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- SPDEF Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_expressed_in_tissue
- Epithelial Tissue [NCIt concept]
- Mammary Gland [NCIt concept]
- Ovary [NCIt concept]
- Prostate Gland [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- ETS Family Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- ETS Domain [NCIt concept]
gene_product_is_element_in_pathway
- Androgen Receptor Regulation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Fate Control [NCIt concept]
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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