Epoetin Zeta - CISMeF

Preferred Label : Epoetin Zeta;

NCIt definition : A recombinant form of the endogenous human cytokine erythropoietin (EPO) with erythropoiesis-stimulating activity. Similar to EPO, epoetin zeta binds to and activates erythropoietin receptors on the surface of committed erythroid progenitors in the bone marrow resulting in their proliferation and differentiation into functional erythrocytes. This may enhance red blood cell counts and hemoglobin levels. Epoetin zeta differs from other epoetins in its glycosylation profile. EPO is a glycosylated polypeptide primarily produced by renal peritubular cells and its synthesis is regulated by a serum oxygenation feedback mechanism.;

CAS number : 604802-70-2;

Drug name : Silapo;

Molecule name : SB309;

Details

Origin ID

C102571;

UMLS CUI

C1997870;

Currated CISMeF NLP mapping
- Epoetin zeta [SMS substance]
- Epoetin zeta (substance) [SNOMED CT concept]
- epoetin zeta [MeSH concept]
- epoetin zeta [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing epoetin zeta (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Epoetin zeta (substance) [SNOMED CT concept]
- Product containing epoetin zeta (medicinal product) [SNOMED CT concept]
- epoetin zeta [MeSH Supplementary Concept]
- epoetin zeta [MeSH concept]
chemical_or_drug_affects_gene_product
- Erythropoietin Receptor [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Receptor Activation Process [NCIt concept]
chemical_or_drug_has_physiologic_effect
- B-Cell Activation [NCIt concept]
- Hematopoiesis Induction [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]
concept_is_in_subset
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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