MAP3K13 wt Allele

Preferred Label : MAP3K13 wt Allele;

NCIt synonyms : MEKK13; MLK; LZK; MGC133196; Mitogen-Activated Protein Kinase Kinase Kinase 13 wt Allele;

NCIt definition : Human MAP3K13 wild-type allele is located in the vicinity of 3q27 and is approximately 206 kb in length. This allele, which encodes mitogen-activated protein kinase kinase kinase 13 protein, plays a role in the modulation of both JNK-dependent signaling and serine/threonine phosphorylation.;

NCIt note : Somatic mutation of the MAP3K13 gene may be associated with breast cancer. (Nature. 2012; 485:doi:10.1038/nature11017.);

GenBank Accession Number : BC031677;

Details

Origin ID

C102524;

UMLS CUI

C3539690;

OMIM relation
- Mitogen-activated protein kinase kinase kinase 13 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3q27 [NCIt concept]
gene_is_element_in_pathway
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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