Alpha-Globin Transcription Factor CP2

Preferred Label : Alpha-Globin Transcription Factor CP2;

NCIt synonyms : Transcription Factor CP2; Transcription Factor LSF; SAA3 Enhancer Factor; Late SV40 Factor; TFCP2;

NCIt definition : Alpha-globin transcription factor CP2 (502 aa, 57 kDa) is encoded by the human TFCP2 gene. This protein plays a role in transcriptional activation.;

NCIt note : Small molecule inhibitors of alpha-globin transcription factor CP2 are a potential treatment for hepatocellular carcinoma. (PNAS. 2012; 109:4503-4508.);

Details

Origin ID

C101802;

UMLS CUI

C3539874;

OMIM relation
- Transcription factor cp2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Regulatory Gene [NCIt concept]
- TFCP2 Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_is_element_in_pathway
- HDAC Class I Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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