Interleukin-33

Preferred Label : Interleukin-33;

NCIt synonyms : NF-HEV; Nuclear Factor from High Endothelial Venules; IL-1F11; Interleukin-1 Family Member 11; IL-33; IL33;

NCIt definition : Interleukin-33 (270 aa, 31 kDa) is encoded by the human IL33 gene. This protein plays a role in the positive regulation of inflammation.;

NCIt note : Interleukin-33 binds to and activates downstream signaling from interleukin-1 receptor-like 1 (IL1RL1; ST2).;

Details

Origin ID

C101779;

UMLS CUI

C1667752;

Automatic exact mappings (from CISMeF team)
- Interleukin 33 [OMIM gene]
- interleukin-33 receptor binding [GO term]
Currated CISMeF NLP mapping
- Interleukin-33 [MeSH Descriptor]
- Interleukin-33 [MeSH concept]
OMIM relation
- Interleukin 33 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- IL33 protein, human [MeSH concept]
- IL33 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Gene [NCIt concept]
- IL33 Gene [NCIt concept]
- Interleukin Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_is_element_in_pathway
- Cytosolic DNA-Sensing Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Receptor Activation [NCIt concept]
- Cytokine Receptor Binding [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Immune Cell Activation Process [NCIt concept]
- Inflammatory Response [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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