" /> H3C2 wt Allele - CISMeF





Preferred Label : H3C2 wt Allele;

NCIt synonyms : Histone Gene Cluster 1, H3b Gene; H3 Histone Family, Member L Gene; H3FL; Histone 1, H3b Gene; H3/l; Histone Gene Cluster 1, H3 Histone Family, Member B Gene; H3 Clustered Histone 2 wt Allele; H3b; Histone Cluster 1, H3b Gene; HIST1 Cluster, H3b Gene; Histone Cluster 1 H3 Family Member B Gene; HIST1H3B;

NCIt related terms : HIST1H3B wt Allele;

NCIt definition : Human H3C2 wild-type allele is located in the vicinity of 6p22.1 and is approximately 1 kb in length. This allele, which encodes histone H3.1 protein, plays a role in the modulation of chromatin structure.;

NCIt note : Somatic mutation of the HIST1H3B gene may be associated with diffuse intrinsic pontine glioma. (Nature Genetics. 2012; 44:251-253.);

GenBank Accession Number : X00090;

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01/06/2025


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