SGK1 wt Allele

Preferred Label : SGK1 wt Allele;

NCIt synonyms : SGK; Serum/Glucocorticoid Regulated Kinase 1 wt Allele; RP1-188K17.1; Serum/Glucocorticoid Regulated Kinase Gene;

NCIt definition : Human SGK1 wild-type allele is located in the vicinity of 6q23 and is approximately 149 kb in length. This allele, which encodes serine/threonine-protein kinase Sgk1 protein, is involved in the modulation of both protein phosphorylation and signaling. Aberrant expression of the gene may be associated with hypertension and diabetic nephropathy.;

GenBank Accession Number : AJ000512;

Détails

Origin ID

C101560;

UMLS CUI

C3538853;

OMIM relation
- Serum/glucocorticoid-regulated kinase 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 6q23 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- ST2 Diffuse Large B-Cell Lymphoma [NCIt concept]
gene_is_element_in_pathway
- Aldosterone-Regulated Sodium Reabsorption Pathway [NCIt concept]
- Class I PI3K Signaling Pathway [NCIt concept]
- FOXO Transcription Factor Family Signaling Pathway [NCIt concept]
- Glucocorticoid Receptor Regulatory Network [NCIt concept]
- Insulin Pathway [NCIt concept]
- mTOR Signaling Pathway PID [NCIt concept]
gene_plays_role_in_process
- Cell Growth Regulation [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cellular Migration Process [NCIt concept]
- Cellular Stress Response [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Regulation of Cell Death Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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