Hairy/Enhancer-of-Split Related with YRPW Motif Protein 1

Preferred Label : Hairy/Enhancer-of-Split Related with YRPW Motif Protein 1;

NCIt synonyms : Hairy-Related Transcription Factor 1; HESR-1; Class B Basic Helix-Loop-Helix Protein 31; HRT-1; HES-Related Repressor Protein 1; Cardiovascular Helix-Loop-Helix Factor 2; Basic Helix-Loop-Helix Protein OAF1; hHRT1; CHF-2; Hairy and Enhancer of Split-Related Protein 1; bHLHb31; HEY1;

NCIt definition : Hairy/enhancer-of-split related with YRPW motif protein 1 (304 aa, 33 kDa) is encoded by the human HEY1 gene. This protein is involved in dimerization with transcription factors to suppress transcription.;

NCIt note : Hairy/enhancer-of-split related with YRPW motif protein 1 binds to the canonical E box sequence 5'-CACGTG-3'. (UniProt);

Details

Origin ID

C101109;

UMLS CUI

C3539570;

OMIM relation
- Hes-related family bhlh transcription factor with yrpw motif 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- HEY1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_biochemical_function
- Transcription Repressor/Corepressor [NCIt concept]
gene_product_has_structural_domain_or_motif
- bHLH Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Protein-Protein Interaction [NCIt concept]
- Signal Transduction Inhibition [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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