TPM3/ALK Fusion Protein

Preferred Label : TPM3/ALK Fusion Protein;

NCIt synonyms : Tropomyosin Alpha-3 Chain/ALK Tyrosine Kinase Receptor Fusion Protein; TPM3-ALK Fusion Protein; TPM3::ALK Fusion Protein;

NCIt definition : A fusion protein encoded by the TPM3/ALK fusion gene. This protein is comprised of most of the tropomyosin alpha-3 chain protein fused to the cytoplasmic domain of the ALK tyrosine kinase receptor protein.;

NCIt note : The TPM3/ALK fusion protein is a constitutively dimerized and activated tyrosine kinase.;

Details

Origin ID

C101084;

UMLS CUI

C3639983;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Fusion Gene [NCIt concept]
- TPM3/ALK Fusion Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- ALK Gene [NCIt concept]
- TPM3 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients