linaclotide - CISMeF

Preferred Label : linaclotide;

MeSH note : an oral guanylate cyclase C agonist linaclotide; 14 amino acid peptide for the potential treatment of constipation-predominant irritable bowel syndrome and chronic idiopathic constipation;

CISMeF synonym : MD-1100 acetate; linaclotide acetate; linzess;

MeSH hyponym : ASP0456;

MeSH CAS label : L-tyrosine, L-cysteinyl-L-cysteinyl-L-alpha-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1- 6),(2- 10),(5- 13)-tris(disulfide);

MeSH Related Number : NSF067KU1M;

Is substance : O;

UNII : N0TXR0XR5X;

Details

Origin ID

C523483;

UMLS CUI

C2000261;

ATC code(s)
- linaclotide [ATC Code]
CISMeF manual mappings
- Linaclotide (substance) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Linaclotide [NCIt concept]
- Product containing linaclotide (medicinal product) [SNOMED CT concept]
MeSH indexing information
- constipation [MeSH Descriptor]
MeSH term(s) associated for indexing
- peptides [MeSH Descriptor]
Pharmacological action(s)
- Guanylyl Cyclase C Agonists [MeSH Descriptor]
Record concept(s)
- ASP-0456 [MeSH concept]
- MD-1100 [MeSH concept]
- MD-1100 acetate [MeSH concept]
- linaclotide [MeSH concept]
- linaclotide acetate [MeSH concept]
- linzess [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Linaclotide [NCIt concept]
- Linaclotide (substance) [SNOMED CT concept]
- Product containing linaclotide (medicinal product) [SNOMED CT concept]
- linaclotide [ATC Code]
Validated automatic mappings to BTNT
- Linaclotide Acetate [NCIt concept]
- linaclotide [ATC Code]

Keyword's position in hierarchy(ies) :

Main resources

You can consult :

recommendations
documents concerning education
documents for patients