TIRAP protein, mouse

Preferred Label : TIRAP protein, mouse;

MeSH note : an adapter protein involved in TLR-4 signal transduction in the inate immune response; acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, resulting in cytokine secretion and the inflammatory response; RefSeq NM_054096;

MeSH synonym : wyatt protein, mouse; MyD88-adapter-like protein, mouse; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein, mouse;

Is substance : O;

Details

Origin ID

C499045;

UMLS CUI

C1101384;

MeSH indexing information
- signal transduction [MeSH Descriptor]
MeSH term(s) associated for indexing
- membrane glycoproteins [MeSH Descriptor]
- receptors, interleukin-1 [MeSH Descriptor]
Record concept(s)
- TIRAP protein, mouse [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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