Preferred Label : 3-ingenyl angelate;
MeSH note : structure in first source;
CISMeF synonym : PEP005; ingenol mebutate; picato;
MeSH synonym : 3-ingenol angelate; ingenol 3-angelate;
MeSH hyponym : PEP-005; PEP 005;
Is substance : O;
Origin ID : C486592;
UMLS CUI : C1452152;
ATC code(s)
- Automatic exact mappings (from CISMeF team)
- MeSH term(s) associated for indexing
- Record concept(s)
- Semantic type(s)
https://ansm.sante.fr/actualites/picato-mebutate-dingenol-le-prac-davril-2020-conclut-a-un-rapport-benefice-risque-defavorable
2020
false
false
false
France
French
drug evaluation
ingenol mebutate
ingenol mebutate
risk assessment
ingenol mebutate
pharmacovigilance
keratosis, actinic
skin neoplasms
3-ingenyl angelate
3-ingenyl angelate
diterpenes
diterpenes
---
PICATO (ingenol mebutate gel, 0.015% and 0.05%) - Product Withdrawal in Canada due
to Potential Increased Risk of Skin Cancer
https://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2020/74193a-fra.php
2020
false
false
false
Canada
French
English
pharmacovigilance note
Safety-Based drug withdrawals
canada
ingenol mebutate
skin neoplasms
risk
ingenol mebutate
administration, cutaneous
keratosis, actinic
3-ingenyl angelate
diterpenes
---
Information Update - Use of the drug Picato may increase the risk of skin cancer
https://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2020/73461a-fra.php
2020
false
false
false
Canada
French
English
pharmacovigilance note
ingenol mebutate
skin neoplasms
risk
administration, cutaneous
keratosis, actinic
3-ingenyl angelate
diterpenes
---
https://ansm.sante.fr/actualites/picato-mebutate-dingenol-suspension-de-lautorisation-de-mise-sur-le-marche-dans-lattente-des-conclusions-de-la-reevaluation-du-rapport-benefice-risque
2020
false
false
false
France
French
Safety-Based drug withdrawals
ingenol mebutate
pharmacovigilance note
administration, cutaneous
skin neoplasms
ingenol mebutate
keratosis, actinic
3-ingenyl angelate
diterpenes
---
https://www.ansm.sante.fr/actualites/picato-mebutate-dingenol-suspension-de-lautorisation-de-mise-sur-le-marche-dans-lattente-des-conclusions-de-la-reevaluation-du-rapport-benefice-risque
2020
false
false
false
France
French
Safety-Based drug withdrawals
ingenol mebutate
risk assessment
skin neoplasms
pharmacovigilance note
guidelines for drug use
administration, cutaneous
ingenol mebutate
carcinoma, squamous cell
keratosis, actinic
3-ingenyl angelate
diterpenes
---
https://ansm.sante.fr/actualites/picato-mebutate-dingenol-retour-dinformation-sur-le-prac-de-septembre-2019
2019
false
false
false
France
French
drug information
administration, cutaneous
ingenol mebutate
risk assessment
keratosis, actinic
ingenol mebutate
carcinoma, squamous cell
3-ingenyl angelate
diterpenes
---
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=66866548
2014
false
false
false
France
French
summary of product characteristics
package leaflet
freezing
gels
ingenol mebutate
3-ingenyl angelate
diterpenes
---
http://base-donnees-publique.medicaments.gouv.fr/extrait.php?specid=65079764
2014
false
false
false
France
French
summary of product characteristics
package leaflet
ingenol mebutate
gels
freezing
3-ingenyl angelate
diterpenes
---
http://www.has-sante.fr/portail/jcms/c_1623645/fr/picato-mebutate-dingenol-chimiotherapie-a-usage-local
http://www.has-sante.fr/portail/jcms/c_1651517/fr/synthese-picato
http://www.has-sante.fr/portail/jcms/c_1623644/fr/picato-26062013-avis-ct12897
2013
false
France
French
administration, cutaneous
treatment outcome
keratosis, actinic
adult
ingenol mebutate
ingenol mebutate
ingenol mebutate
3-ingenyl angelate
3-ingenyl angelate
randomized controlled trials as topic
comparative study
follow-up studies
insurance, health, reimbursement
guidelines for drug use
evaluation of the transparency committee
diterpenes
diterpenes
---
http://www.has-sante.fr/portail/jcms/c_1623645/fr/picato
2013
false
France
French
evaluation of the transparency committee
ingenol mebutate
3-ingenyl angelate
ingenol mebutate
administration, cutaneous
keratosis, actinic
3-ingenyl angelate
ingenol mebutate
insurance, health, reimbursement
adult
treatment outcome
diterpenes
diterpenes
---
https://www.ema.europa.eu/medicines/human/EPAR/Picato
2012
false
United Kingdom
French
English
ingenol mebutate
drug approval
europe
treatment outcome
gels
adult
keratosis, actinic
administration, cutaneous
summary of product characteristics
package leaflet
drug evaluation
syndication feed
diterpenes
diterpenes
other chemotherapeutics
aged
pregnancy
breast feeding
controlled clinical trials as topic
drug evaluation, preclinical
3-ingenyl angelate
3-ingenyl angelate
ingenol mebutate
---
