N2-((2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-L-alaninamide

Preferred Label : N2-((2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-L-alaninamide;

MeSH note : a gamma-secretase inhibitor;

CISMeF synonym : LY 411575; LY 450139; N2-(2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-(5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)alaninamide; semagacestat;

MeSH hyponym : LY411575; LY-411575; LY411,575; LY 411,575; LY-411,575;

Related MeSH term : LY450139;

Is substance : O;

Details

Origin ID

C484278;

UMLS CUI

C1563677;

Automatic exact mappings (from CISMeF team)
- Semagacestat [NCIt concept]
MeSH indexing information
- amyloid precursor protein secretases [MeSH Descriptor]
MeSH term(s) associated for indexing
- alanine [MeSH Descriptor]
- azepines [MeSH Descriptor]
Pharmacological action(s)
- Gamma Secretase Inhibitors and Modulators [MeSH Descriptor]
Record concept(s)
- LY 411575 [MeSH concept]
- LY 450139 [MeSH concept]
- N2-((2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-L-alaninamide [MeSH concept]
- N2-(2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-(5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)alaninamide [MeSH concept]
- Semagacestat [MeSH concept]
Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Organic Chemical [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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