" /> Gamma Secretase Inhibitors and Modulators - CISMeF





Preferred Label : Gamma Secretase Inhibitors and Modulators;

MeSH definition : Agents that suppress GAMMA-SECRETASE by inhibiting or modulating its activities. Targeted enzymatic activities include its involvement in accumulation of toxic AMYLOID BETA-PEPTIDES (e.g., Aβ42) in ALZHEIMER DISEASE and activation of NOTCH RECEPTOR mediated SIGNAL PATHWAYS in certain cancer types.;

MeSH synonym : GS Inhibitors and Modulators;

MeSH hyponym : Secretase Modulators, Gamma; GS Modulators; Secretase Inhibitors, Gamma; GS Inhibitors;

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Agents that suppress GAMMA-SECRETASE by inhibiting or modulating its activities. Targeted enzymatic activities include its involvement in accumulation of toxic AMYLOID BETA-PEPTIDES (e.g., Aβ42) in ALZHEIMER DISEASE and activation of NOTCH RECEPTOR mediated SIGNAL PATHWAYS in certain cancer types.

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27/07/2025


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