AML1-MDS1-EVI1 fusion protein, human

Preferred Label : AML1-MDS1-EVI1 fusion protein, human;

MeSH note : leukemia-associated fusion gene AML1/MDS1/EVI1 (AME) encodes a chimeric transcription factor that results from the (3;21)(q26;q22) translocation; this translocation is observed in patients with therapy-related myelodysplastic syndrome (MDS), with chronic myelogenous leukemia during the blast crisis (CML-BC), and with de novo or therapy-related acute myeloid leukemia (AML);

MeSH synonym : AML1-MDS1-EVI1 protein, human;

Is substance : O;

Details

Origin ID

C460199;

UMLS CUI

C1137745;

MeSH term(s) associated for indexing
- core binding factor alpha 2 subunit [MeSH Descriptor]
- oncogene proteins, fusion [MeSH Descriptor]
- repressor proteins [MeSH Descriptor]
Record concept(s)
- AML1-MDS1-EVI1 fusion protein, human [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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