Preferred Label : entacapone;

MeSH note : structure given in first source;

CISMeF synonym : OR 611; comtan; comtess; novartis brand of entacapone; orion brand of entacapone;

MeSH synonym : 2-cyano-N,N-diethyl-3-(3,4-dihydroxy-5-nitrophenyl)propenamide;

MeSH hyponym : OR-611;

MeSH CAS label : (E)-2-cyano-3-(3,4-dihydroxy-5-nitro-phenyl)-N,N-diethyl-prop-2-enamide;

MeSH Related Number : 116314-67-1 (entacapone);

Registry Number MeSH : 116314-67-1;

Is substance : O;

UNII : 4975G9NM6T;

InChIKey : JRURYQJSLYLRLN-BJMVGYQFSA-N;

Details


Main resources

You can consult :


https://www.has-sante.fr/jcms/p_3330854/fr/lecigimon-levodopa/-carbidopa/-entacapone-maladie-de-parkinson-a-un-stade-avance
2022
false
false
false
France
carbidopa
drug combinations
levodopa
insurance, health, reimbursement
treatment outcome
parkinson disease
antiparkinson agents
levodopa, decarboxylase inhibitor and comt inhibitor
Product containing only carbidopa and entacapone and levodopa (medicinal product)
Intestinal Gel Dosage Form
Intestinal Route of Administration
evaluation of the transparency committee
entacapone

---
https://www.has-sante.fr/jcms/p_3402036/fr/lecigimon-levodopa/carbidopa/entacapone-maladie-de-parkinson
2022
false
false
false
France
treatment outcome
insurance, health, reimbursement
drug combinations
carbidopa
levodopa
entacapone
levodopa, decarboxylase inhibitor and comt inhibitor
Intestinal Route of Administration
gels
Motor fluctuations
evaluation of the transparency committee
parkinson disease

---
https://www.has-sante.fr/jcms/p_3193437/fr/comtan
2020
false
false
false
France
entacapone
insurance, health, reimbursement
evaluation of the transparency committee
entacapone
catechols
nitriles

---
https://www.ansm.sante.fr/actualites/difficultes-dapprovisionnement-en-entacapone-comtan-et-generique-mylan-recommandations-pour-les-patients-et-les-professionnels-de-sante
2020
false
false
false
France
French
guidelines for drug use
entacapone
entacapone
pharmacovigilance note
administration, oral
entacapone
Catechol O-Methyltransferase Inhibitors
Catechol O-Methyltransferase Inhibitors
parkinson disease
catechols
nitriles
catechols
nitriles

---
https://www.ema.europa.eu/medicines/human/EPAR/corbilta-previously-levodopacarbidopaentacapone-sandoz
2013
false
United Kingdom
French
English
Stalevo
Stalevo
entacapone
entacapone
drug approval
europe
treatment outcome
levodopa, decarboxylase inhibitor and comt inhibitor
Product containing carbidopa and entacapone and levodopa (medicinal product)
dopamine agents
dopamine agents
administration, oral
drug combinations
antiparkinson agents
antiparkinson agents
parkinson disease
adult
dopa decarboxylase
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
summary of product characteristics
package leaflet
drug evaluation
syndication feed
catechols
catechols
nitriles
nitriles
Catechol O-Methyltransferase Inhibitors
Catechol O-Methyltransferase Inhibitors

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=67386662
2012
France
summary of product characteristics
package leaflet
tablets
entacapone

---
https://www.ema.europa.eu/medicines/human/EPAR/Comtan
2012
false
United Kingdom
English
French
syndication feed
Catechol O-Methyltransferase Inhibitors
Catechol O-Methyltransferase Inhibitors
Contraindications, Procedure
nitriles
antiparkinson agents
parkinson disease
catechols
nitriles
antiparkinson agents
treatment outcome
drug evaluation
catechols
nitriles
antiparkinson agents
tablets
administration, oral
adult
aged
nitriles
catechols
antiparkinson agents
drug interactions
pregnancy
breast feeding
catechols
nitriles
antiparkinson agents
catechols
nitriles
antiparkinson agents
drug labeling
drug approval
catechols
entacapone
entacapone
catechols
nitriles
summary of product characteristics
package leaflet
drug evaluation
Contraindications, Drug

---
https://www.ema.europa.eu/medicines/human/EPAR/Comtess
2012
false
United Kingdom
French
English
syndication feed
Catechol O-Methyltransferase Inhibitors
adult
aged
drug interactions
drug labeling
drug approval
pregnancy
breast feeding
parkinson disease
treatment outcome
drug evaluation
tablets
administration, oral
drug therapy, combination
entacapone
entacapone
Product containing entacapone (medicinal product)
drug evaluation
summary of product characteristics
package leaflet
antiparkinson agents
catechols
enzyme inhibitors
nitriles
antiparkinson agents
catechols
nitriles

---
https://www.ema.europa.eu/medicines/human/EPAR/levodopacarbidopaentacapone-orion
2012
false
United Kingdom
French
English
package leaflet
summary of product characteristics
syndication feed
Catechol O-Methyltransferase Inhibitors
Catechol O-Methyltransferase Inhibitors
catechols
catechols
nitriles
nitriles
dopamine agents
dopamine agents
drug evaluation, preclinical
carbidopa
levodopa
Stalevo
entacapone
drug combinations
Stalevo
levodopa
carbidopa
entacapone
levodopa, decarboxylase inhibitor and comt inhibitor
parkinson disease
administration, oral
drug approval
adult
antiparkinson agents
antiparkinson agents
drug interactions
pregnancy
breast feeding
treatment outcome
dopa decarboxylase

---
https://www.ema.europa.eu/medicines/human/EPAR/Stalevo
2012
United Kingdom
English
French
syndication feed
drug combinations
parkinson disease
tablets
administration, oral
drug evaluation
treatment outcome
adult
aged
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
drug labeling
drug approval
Stalevo
entacapone
levodopa, decarboxylase inhibitor and comt inhibitor
nitriles
package leaflet
summary of product characteristics
drug evaluation
antiparkinson agents
antiparkinson agents
carbidopa
catechols
levodopa
carbidopa
catechols
levodopa

---
http://www.has-sante.fr/portail/jcms/c_399264/comtan-200mg-comprime-pellicule-boites-de-60-et-de-100
http://www.has-sante.fr/portail/display.jsp?id=c_468598
http://www.has-sante.fr/portail/jcms/c_1281291/comtan
http://www.has-sante.fr/portail/upload/docs/application/pdf/2012-08/comtan_18072012_avis_ct_11559.pdf
2012
false
France
French
Catechol O-Methyltransferase Inhibitors
parkinson disease
entacapone
administration, oral
antiparkinson agents
entacapone
catechols
nitriles
insurance, health, reimbursement
evaluation of the transparency committee

---
https://www.ema.europa.eu/medicines/human/EPAR/Entacapone-Orion
2012
false
United Kingdom
French
English
summary of product characteristics
package leaflet
syndication feed
Catechol O-Methyltransferase Inhibitors
Catechol O-Methyltransferase Inhibitors
entacapone
entacapone
drug approval
treatment outcome
entacapone
catechols
nitriles
nitriles
catechols
antiparkinson agents
antiparkinson agents
administration, oral
adult
drug therapy, combination
drug interactions
pregnancy
breast feeding

---
https://www.ema.europa.eu/medicines/human/EPAR/Entacapone-Teva
2011
false
United Kingdom
English
French
syndication feed
Catechol O-Methyltransferase Inhibitors
Catechol O-Methyltransferase Inhibitors
catechols
entacapone
entacapone
catechols
nitriles
nitriles
antiparkinson agents
antiparkinson agents
administration, oral
drugs, generic
entacapone
drug approval
adult
breast feeding
pregnancy
drug interactions
aged
drug evaluation
parkinson disease
drug therapy, combination
catechols
nitriles
drug evaluation
package leaflet
summary of product characteristics

---
https://www.cadth.ca/sites/default/files/pdf/134_entacapone_cetap_f.pdf
https://www.cadth.ca/sites/default/files/pdf/134_entacapone_cetap_e.pdf
2000
false
Canada
French
English
Catechol O-Methyltransferase Inhibitors
entacapone
catechols
nitriles
antiparkinson agents
parkinson disease
drug therapy, combination
canada
treatment outcome
Evidence-Based medicine
entacapone
catechols
nitriles
drug evaluation

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04/06/2024


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