Preferred Label : benfluorex;

MeSH note : RN given refers to parent cpd without isomeric designation; structure;

CISMeF synonym : 23642-66-2 (benfluorex hydrochloride); JP 992; S 780; SE 780; biopharma brand of benfluorex hydrochloride; mediator trade name of benfluorex hydrochloride; modulator trade name of benfluorex hydrochloride; servier brand of benfluorex hydrochloride;

MeSH synonym : benfluramate;

MeSH hyponym : 780 SE; 1-(2-trifluoromethylphenyl)-2-(benzoyloxyethyl)aminopropane HCl;

MeSH CAS label : N-(2-benzoyloxyethyl)norfenfluramine;

MeSH Related Number : benfluorex hydrochloride, ( -)-isomer; benfluorex maleate; benfluorex hydrochloride; benfluorex, methanesulfonate salt; 76958-27-5 (unspecified maleate); 22471-86-9 (HCl( -)-isomer); 23602-78-0 (benfluorex); 23642-66-2 (HCl); 51775-23-6 (methanesulfonate salt); X7O165XZ00;

Libelles Related CAS CISMeF : ménadione;

Registry Number MeSH : 23602-78-0;

Related CAS MeSH : 22471-86-9 (benfluorex hydrochloride, ( -)-isomer); 76958-27-5 (benfluorex maleate); 51775-23-6 (benfluorex, methanesulfonate salt); X7O165XZ00 (benfluorex hydrochloride);

related registry number list (CISMeF) : 22471-86-9 (HCl( -)-isomer); 23642-66-2 (HCl); 51775-23-6 (methanesulfonate salt); 76958-27-5 (unspecified maleate);

Codes EINECS : 245-777-9;

Is substance : O;

UNII : 403FO0NQG3;

InChIKey : CJAVTWRYCDNHSM-UHFFFAOYSA-N;

Details


Main resources

You can consult :


https://ansm.sante.fr/actualites/benfluorex-conclusions-du-rapport-2020-2023-de-surveillance-des-cas-dhypertension-arterielle-pulmonaire
2025
false
false
false
France
French
technical report
health surveys
hypertension, pulmonary
benfluorex
pharmacovigilance
benfluorex

---
https://ansm.sante.fr/actualites/benfluorex-bilan-du-suivi-des-cas-dhypertension-arterielle-pulmonaire
2022
false
false
false
France
French
drug evaluation
pharmacovigilance
benfluorex
france
hypertension, pulmonary
epidemiological monitoring

---
http://www.theses.fr/2018STRAG054
2018
France
dissertations, academic
Pathology
Pathology
drug therapy
benfluorex
heart valve diseases
accidents
Pathology
drug, nos
Pathology
Pathology
Pathology
Pathology
pharmaceutical preparations
accident, nos
Treatments
therapeutics
Disorders
Therapeutics

---
http://www.franceculture.fr/emission-revolutions-medicales-y-a-t-il-des-medicaments-mortels-affaire-du-mediator-2015-09-29
2015
false
false
false
France
French
radio broadcast
benfluorex
appetite depressants
anti-obesity agents
compensation and redress
inappropriate prescribing

---
http://www.victimes-isomeride.asso.fr/
http://www.avim.fr/
France
French
patient advocacy
patient rights
fenfluramine
benfluorex
fenfluramine
association of patients
hotlines

---
https://sante.gouv.fr/ministere/documentation-et-publications-officielles/rapports/sante/article/rapport-de-sa-mission-relative-aux-recommandations-formulees-en-matiere-d
http://sante.gouv.fr//IMG/pdf/Rapport_Claire_Favre_indemnisation_des_victimes_du_Mediator_-_22_06_11_2_.pdf
2012
false
France
French
technical report
Cardiotoxicity
benfluorex
fenfluramine
heart valve diseases
expert testimony
consultants

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=65580266
2012
France
summary of product characteristics
package leaflet
benfluorex
tablets
drug approval

---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=61140629
2012
France
summary of product characteristics
package leaflet
tablets
drug approval
benfluorex

---
https://www.legifrance.gouv.fr/jo_pdf.do?id=JORFTEXT000024540969
2011
false
true
false
France
fenfluramine
fenfluramine
legislation
compensation and redress
benfluorex

---
https://medias.vie-publique.fr/data_storage_s3/rapport/pdf/114000028.pdf
https://medias.vie-publique.fr/data_storage_s3/rapport/pdf/114000029.pdf
2011
false
France
French
Cardiotoxicity
benfluorex
fenfluramine
fenfluramine
hypertension, pulmonary
heart valve diseases
administration, oral
drug approval
appetite depressants
hypolipidemic agents
adverse drug reaction reporting systems
hypertriglyceridemia
diabetes mellitus, type 2
benfluorex
overweight
technical report
drug information

---
https://assurance-maladie.ameli.fr/etudes-et-donnees/2009-2010-benfluorex-risques-valvulopathie-cardiaque-deces
2010
France
technical report
risk
death
benfluorex
heart valve diseases
benfluorex
heart valve disorder, nos

---
http://www.lecrat.eu/?s=Benfluorex
2009
France
French
fenfluramine
pregnancy
hypolipidemic agents
benfluorex
benfluorex
drug information

---
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01/05/2025


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