Preferred Label : fenfluramine;

MeSH definition : A centrally active drug that apparently both blocks serotonin uptake and provokes transport-mediated serotonin release.;

CISMeF synonym : 404-82-0 (Fenfluramine hydrochloride); robins brand of fenfluramine hydrochloride;

MeSH hyponym : fenfluramine hydrochloride, R-Isomer; fenfluramine hydrochloride, ( -)-Isomer; fenfluramine hydrochloride; isomeride; fenfluramine, ( -)-Isomer; pondimin; fenfluramine, R-Isomer; Fenfluramine Hydrochloride, R Isomer; Fenfluramine, R Isomer; Hydrochloride, Fenfluramine;

MeSH CAS label : benzeneethanamine, N-ethyl-alpha-methyl-3-(trifluoromethyl)-;

MeSH Related Number : fenfluramine hydrochloride, ( -)-Isomer; fenfluramine, ( -)-Isomer; fenfluramine, R-Isomer; fenfluramine hydrochloride; fenfluramine hydrochloride, R-Isomer; 16105-77-4 (( -)-isomer, HCl); 3616-78-2 (R-isomer, HCl); 37577-24-5 (R-isomer); 404-82-0 (HCl); 458-24-2 (Fenfluramine); 5220-89-3 (( -)-isomer); 3KC089243P;

Registry Number MeSH : 458-24-2;

Related CAS MeSH : 16105-77-4 (Fenfluramine hydrochloride, ( -)-Isomer); 5220-89-3 (Fenfluramine, ( -)-Isomer); 37577-24-5 (Fenfluramine, R-Isomer); 3616-78-2 (Fenfluramine hydrochloride, R-Isomer); 3KC089243P (Fenfluramine hydrochloride);

Wikipedia link : https://en.wikipedia.org/wiki/Fenfluramine;

Codes EINECS : 207-276-3;

Is substance : O;

UNII : 2DS058H2CF;

InChIKey : DBGIVFWFUFKIQN-UHFFFAOYSA-N;

Details


Main resources

You can consult :

A centrally active drug that apparently both blocks serotonin uptake and provokes transport-mediated serotonin release.

https://ansm.sante.fr/tableau-marr/fenfluramine
2024
false
false
false
France
French
administration, oral
risk management
guidelines for drug use
pharmacovigilance note
fenfluramine
fenfluramine
continuity of patient care
drug monitoring
hypertension, pulmonary
Drug-Related side effects and adverse reactions
heart valve diseases
patients guideline
Off-Label use

---
https://www.has-sante.fr/jcms/p_3561260/fr/fintepla-fenfluramine-epilepsie
2024
false
false
false
France
administration, oral
treatment outcome
insurance, health, reimbursement
Lennox Gastaut Syndrome
Drug Resistant Epilepsy
child
Lennox-Gastaut Syndrome, Intractable, with Status Epilepticus
evaluation of the transparency committee
fenfluramine
drug therapy, combination

---
https://www.has-sante.fr/jcms/p_3269738/fr/fintepla-fenfluramine
2021
false
false
false
France
French
evaluation of the transparency committee
administration, oral
treatment outcome
insurance, health, reimbursement
child
epilepsy, myoclonic, infantile, severe
fenfluramine
guidelines for drug use
fenfluramine
fenfluramine
epilepsies, myoclonic

---
https://www.ema.europa.eu/en/medicines/human/EPAR/fintepla
2021
false
false
false
Netherlands
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
fenfluramine
fenfluramine
fenfluramine
drug therapy, combination
child
adolescent
adult
epilepsy, myoclonic, infantile, severe
orphan drug production
administration, oral
Selective Serotonin Reuptake Inhibitors
Selective Serotonin Reuptake Inhibitors
product surveillance, postmarketing
drug interactions
pregnancy
breast feeding
drug evaluation, preclinical
Dravet syndrome
epilepsies, myoclonic

---
https://sante.gouv.fr/ministere/documentation-et-publications-officielles/rapports/sante/article/rapport-de-sa-mission-relative-aux-recommandations-formulees-en-matiere-d
http://sante.gouv.fr//IMG/pdf/Rapport_Claire_Favre_indemnisation_des_victimes_du_Mediator_-_22_06_11_2_.pdf
2012
false
France
French
technical report
Cardiotoxicity
benfluorex
fenfluramine
heart valve diseases
expert testimony
consultants

---
http://www.victimes-isomeride.asso.fr/
http://www.avim.fr/
France
French
patient advocacy
patient rights
fenfluramine
benfluorex
fenfluramine
association of patients
hotlines

---
https://medias.vie-publique.fr/data_storage_s3/rapport/pdf/114000028.pdf
https://medias.vie-publique.fr/data_storage_s3/rapport/pdf/114000029.pdf
2011
false
France
French
Cardiotoxicity
benfluorex
fenfluramine
fenfluramine
hypertension, pulmonary
heart valve diseases
administration, oral
drug approval
appetite depressants
hypolipidemic agents
adverse drug reaction reporting systems
hypertriglyceridemia
diabetes mellitus, type 2
benfluorex
overweight
technical report
drug information

---
http://www.lecrat.eu/?s=Benfluorex
2009
France
French
fenfluramine
pregnancy
hypolipidemic agents
benfluorex
benfluorex
drug information

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02/05/2025


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