Heparin-binding EGF-like Growth Factor

Preferred Label : Heparin-binding EGF-like Growth Factor;

MeSH definition : An EGF family member that is expressed in a variety of hematopoietic, endothelial, vascular smooth muscle, and epithelial cells. It is synthesized as a transmembrane protein which is cleaved by proteases to produce the secreted form of the protein which has specificity for the EGF RECEPTOR and the ERBB-4 RECEPTOR. The membrane-bound form of the protein has been identified as the receptor which binds to and allows DIPHTHERIA TOXIN to enter cells.;

MeSH synonym : Heparin binding EGF like Growth Factor; HB-EGF; HB EGF; Heparin-binding EGF-like Growth-Factor;

MeSH hyponym : Heparin-binding Epidermal Growth Factor-like Growth Factor Precursor Protein; short form HB-EGF; HB-EGF, Short Form; Short Form HB EGF; SF HB-EGF; SF HB EGF; Heparin binding Epidermal Growth Factor like Growth Factor Precursor Protein; Receptor, Diphtheria Toxin; HB-EGF Precursor; HB EGF Precursor; Diphtheria Toxin Receptor; Toxin Receptor, Diphtheria; Diphtheria Toxin Receptors; Receptors, Diphtheria Toxin; Toxin Receptors, Diphtheria;

Details

Origin ID

D066257;

UMLS CUI

C0166825;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- HBEGF Gene [NCIt concept]
- HBEGF wt Allele [NCIt concept]
- Heparin-Binding EGF-Like Growth Factor [NCIt concept]
- Heparin-binding egf-like growth factor [OMIM gene]
- heparin binding EGF like growth factor [HGNC gene]
Record concept(s)
- Heparin-binding EGF-like Growth Factor [MeSH concept]
- Heparin-binding Epidermal Growth Factor-like Growth Factor Precursor Protein [MeSH concept]
- short form HB-EGF [MeSH concept]
Related MeSH Supplementary Concept(s)
- HBEGF protein, human [MeSH Supplementary Concept]
- Hbegf protein, mouse [MeSH Supplementary Concept]
- Hbegf protein, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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