Cytochrome P-450 CYP2B6

Preferred Label : Cytochrome P-450 CYP2B6;

Obsolete resource : false;

MeSH definition : A cytochrome P450 enzyme subtype that oxidizes a diverse array of XENOBIOTICS. The expression of CYP2B6 varies widely between individuals which is due to the high rate of GENETIC POLYMORPHISMS. Examples of drugs metabolized by CYP2B6 include BUPROPION; efavirenz; CYCLOPHOSPHAMIDE; and MEPERIDINE.;

MeSH synonym : CYP2B6, Cytochrome P-450; Cytochrome P 450 CYP2B6; P-450 CYP2B6, Cytochrome; CYP2B6; Cytochrome P450 2B6; P450 2B6, Cytochrome; 1,4-Cineole 2-exo-Monooxygenase; 1,4 Cineole 2 exo Monooxygenase; 2-exo-Monooxygenase, 1,4-Cineole; CYPIIB6;

Registry Number MeSH : EC 1.14.14.1;

UNII : EC 1.14.14.1;

Details

Origin ID

D065702;

UMLS CUI

C1828468;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- CYP2B6 Gene [NCIt concept]
- Cytochrome P450 2A6 [NCIt concept]
- Cytochrome p450 CYP2B6 enzyme (substance) [SNOMED CT concept]
- Cytochrome p450, subfamily iib, polypeptide 6 [OMIM gene]
- cytochrome P450 family 2 subfamily B member 6 [ORDO Gene]
Currated CISMeF NLP mapping
- Cytochrome P450 2B6 [NCIt concept]
Record concept(s)
- Cytochrome P-450 CYP2B6 [MeSH concept]
Related MeSH Supplementary Concept(s)
- CYP2B6 protein, human [MeSH Supplementary Concept]
Related MeSH term(s)
- Cytochrome P-450 CYP2B6 Inhibitors [MeSH Descriptor]
See also (suggested by CISMeF)
- Cytochrome P-450 CYP2B6 Inducers [MeSH Descriptor]
- Cytochrome P-450 CYP2B6 Inhibitors [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Cytochrome p450 CYP2B6 enzyme (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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