Hypoxia-Inducible Factor-Proline dioxygenases

Preferred Label : Hypoxia-Inducible Factor-Proline dioxygenases;

MeSH definition : Dioxygenase enzymes that specifically hydroxylate a PROLINE residue on the HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. They are OXYGEN-dependent enzymes that play an important role in mediating cellular adaptive responses to HYPOXIA.;

MeSH synonym : dioxygenases, Hypoxia-Inducible Factor-Proline; Factor-Proline dioxygenases, Hypoxia-Inducible; hypoxia inducible factor proline dioxygenases; HIF Prolyl-4-Hydroxylases; HIF prolyl 4 hydroxylases; Prolyl-4-Hydroxylases, HIF; Hypoxia-Inducible Factor-Proline dioxygenase; dioxygenase, Hypoxia-Inducible Factor-Proline; Factor-Proline dioxygenase, Hypoxia-Inducible; hypoxia inducible factor proline dioxygenase; HIF Prolyl-4-Hydroxylase; HIF prolyl 4 hydroxylase; Prolyl-4-Hydroxylase, HIF;

CISMeF acronym : HIF-PH;

MeSH hyponym : Hypoxia-Inducible factor prolyl hydroxylase 2; Hypoxia-Inducible factor prolyl hydroxylase 3; Hypoxia-Inducible factor prolyl hydroxylase 1; Hypoxia Inducible Factor Prolyl Hydroxylase 2; Egl Nine Homolog 1 Protein; Hypoxia Inducible Factor Prolyl Hydroxylase 3; Egl Nine Homolog 3 Protein; Hypoxia Inducible Factor Prolyl Hydroxylase 1; Egl Nine Homolog 2 Protein;

MeSH Related Number : Hypoxia-Inducible factor prolyl hydroxylase 2; Hypoxia-Inducible factor prolyl hydroxylase 3; Hypoxia-Inducible factor prolyl hydroxylase 1; EC 1.14.11.29;

Registry Number MeSH : EC 1.14.11.29;

Related CAS MeSH : EC 1.14.11.29 (Hypoxia-Inducible factor prolyl hydroxylase 2); EC 1.14.11.29 (Hypoxia-Inducible factor prolyl hydroxylase 3); EC 1.14.11.29 (Hypoxia-Inducible factor prolyl hydroxylase 1);

Is substance : O;

UNII : EC 1.14.11.29;

Details

Origin ID

D064799;

UMLS CUI

C3658213;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Egl Nine Homolog 1 [NCIt concept]
- Egl Nine Homolog 2 [NCIt concept]
Indexing information
- TP0463518 [MeSH Supplementary Concept]
- roxadustat [MeSH Supplementary Concept]
Record concept(s)
- Hypoxia-Inducible Factor-Proline dioxygenases [MeSH concept]
- Hypoxia-Inducible factor prolyl hydroxylase 1 [MeSH concept]
- Hypoxia-Inducible factor prolyl hydroxylase 2 [MeSH concept]
- Hypoxia-Inducible factor prolyl hydroxylase 3 [MeSH concept]
Related MeSH Supplementary Concept(s)
- EGLN1 protein, human [MeSH Supplementary Concept]
- EGLN2 protein, human [MeSH Supplementary Concept]
- EGLN3 protein, human [MeSH Supplementary Concept]
- Egln1 protein, mouse [MeSH Supplementary Concept]
- Egln1 protein, rat [MeSH Supplementary Concept]
- Egln3 protein, rat [MeSH Supplementary Concept]
See also (suggested by CISMeF)
- roxadustat [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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