receptor tyrosine kinase-like orphan receptors

Preferred Label : receptor tyrosine kinase-like orphan receptors;

MeSH definition : A family of cell surface receptors that were originally identified by their structural homology to neurotropic TYROSINE KINASES and referred to as orphan receptors because the associated ligand and signaling pathways were unknown. Evidence for the functionality of these proteins has been established by experiments showing that disruption of the orphan receptor genes results in developmental defects.;

MeSH synonym : neurotrophic tyrosine kinase, receptor-related proteins; NTRKR receptors; ROR tyrosine kinase receptors; neurotrophic tyrosine kinase, receptor related proteins; receptor tyrosine kinase like orphan receptors; Receptor Tyrosine Kinase-like Orphan Receptor; Receptor Tyrosine Kinase like Orphan Receptor;

MeSH hyponym : receptor tyrosine kinase-like orphan receptor 2; receptor tyrosine kinase-like orphan receptor 1; Receptor Tyrosine Kinase like Orphan Receptor 2; ROR2 Tyrosine Kinase; Kinase, ROR2 Tyrosine; Receptor Tyrosine Kinase like Orphan Receptor 1; ROR1 Tyrosine Kinase; Tyrosine Kinase, ROR1;

MeSH Related Number : receptor tyrosine kinase-like orphan receptor 2; receptor tyrosine kinase-like orphan receptor 1; EC 2.7.10.1;

Registry Number MeSH : EC 2.7.10.1;

Related CAS MeSH : EC 2.7.10.1 (Receptor tyrosine kinase-like orphan receptor 2); EC 2.7.10.1 (Receptor tyrosine kinase-like orphan receptor 1);

MeSH annotation : do not confuse with ORPHAN NUCLEAR RECEPTORS;

Is substance : O;

UNII : EC 2.7.10.1;

Details

Origin ID

D057050;

UMLS CUI

C2717962;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Receptor tyrosine kinase-like orphan receptor 1 [OMIM gene]
- Receptor tyrosine kinase-like orphan receptor 2 [OMIM gene]
- Tyrosine-Protein Kinase Transmembrane Receptor ROR1 [NCIt concept]
- Tyrosine-Protein Kinase Transmembrane Receptor ROR2 [NCIt concept]
- receptor tyrosine kinase like orphan receptor 1 [ORDO Gene]
- receptor tyrosine kinase like orphan receptor 1 [HGNC gene]
- receptor tyrosine kinase like orphan receptor 2 [HGNC gene]
- receptor tyrosine kinase like orphan receptor 2 [ORDO Gene]
Record concept(s)
- receptor tyrosine kinase-like orphan receptor 1 [MeSH concept]
- receptor tyrosine kinase-like orphan receptor 2 [MeSH concept]
- receptor tyrosine kinase-like orphan receptors [MeSH concept]
Related MeSH Supplementary Concept(s)
- CAM-1 protein, C elegans [MeSH Supplementary Concept]
- ROR1 protein, human [MeSH Supplementary Concept]
- ROR2 protein, human [MeSH Supplementary Concept]
- Ror1 protein, mouse [MeSH Supplementary Concept]
- Ror1 protein, rat [MeSH Supplementary Concept]
- Ror2 protein, Xenopus [MeSH Supplementary Concept]
- Ror2 protein, mouse [MeSH Supplementary Concept]
- Ror2 protein, rat [MeSH Supplementary Concept]
- Ror2 protein, zebrafish [MeSH Supplementary Concept]
- ror1 protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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