nuclear receptor Co-Repressor 2

Preferred Label : nuclear receptor Co-Repressor 2;

MeSH definition : A nuclear co-repressor protein that shows specificity for RETINOIC ACID RECEPTORS and THYROID HORMONE RECEPTORS. The dissociation of this co-repressor from nuclear receptors is generally ligand-dependent, but can also occur by way of its phosphorylation by members of the MAP KINASE SIGNALING SYSTEM. The protein contains two nuclear receptor interaction domains and four repressor domains and is closely-related in structure to NUCLEAR RECEPTOR CO-REPRESSOR 1.;

MeSH synonym : co-repressor, TRAC; SMRT co repressor; SMRT co-repressor; T3 receptor associating factor; TRAC co repressor; TRAC co-repressor; T3 receptor-associating factor; receptor-associating factor, T3; silencing mediator of retinoic acid and thyroid hormone receptor; co-repressor, SMRT; nuclear receptor co repressor 2;

Is substance : O;

Details

Origin ID

D056985;

UMLS CUI

C0382270;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Nuclear Receptor Corepressor 2 [NCIt concept]
Record concept(s)
- nuclear receptor Co-Repressor 2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- NCOR2 protein, human [MeSH Supplementary Concept]
- Ncor2 protein, mouse [MeSH Supplementary Concept]
- Ncor2 protein, rat [MeSH Supplementary Concept]
- silencing mediator of retinoic acid and thyroid hormone receptors, rat [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Nuclear Receptor Corepressor 2 [NCIt concept]

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