MeSH definition : Proteins that enhance gene expression when associated with ligand bound activated
NUCLEAR RECEPTORS. The coactivators may act through an enzymatic process that affects
the rate of transcription or the structure of chromatin. Alternatively nuclear receptor
coactivators can function as adaptor proteins that bring nuclear receptors into close
proximity with transcriptional complexes.;
Proteins that enhance gene expression when associated with ligand bound activated
NUCLEAR RECEPTORS. The coactivators may act through an enzymatic process that affects
the rate of transcription or the structure of chromatin. Alternatively nuclear receptor
coactivators can function as adaptor proteins that bring nuclear receptors into close
proximity with transcriptional complexes.