protein tyrosine phosphatase, Non-Receptor type 11

Preferred Label : protein tyrosine phosphatase, Non-Receptor type 11;

MeSH definition : A subtype of non-receptor protein tyrosine phosphatases that contain two SRC HOMOLOGY DOMAINS. Mutations in the gene for protein tyrosine phosphatase, non-receptor type 11 are associated with NOONAN SYNDROME.;

MeSH synonym : protein tyrosine phosphatase 2c; shptp2; shp2 phosphatase; protein tyrosine phosphatase ptp3; protein-tyrosine-phosphatase 2c; shp-2 tyrosine phosphatase; shp 2 tyrosine phosphatase; tyrosine phosphatase, shp-2; phosphatase, shp2; Phosphotyrosine Phosphatase Syp; protein tyrosine phosphatase, non receptor type 11; SHP-2 Protein-Tyrosine phosphatase;

CISMeF synonym : phosphatase, shp-2 tyrosine; protein-tyrosine phosphatase, sh; sh protein tyrosine phosphatase; sh protein-tyrosine phosphatase;

Registry Number MeSH : EC 3.1.3.48;

Is substance : O;

UNII : EC 3.1.3.48;

Details

Origin ID

D054592;

UMLS CUI

C0656342;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Cyclin-Dependent Kinase Inhibitor 3 [NCIt concept]
- Dual Specificity Protein Phosphatase 1 [NCIt concept]
- Dual Specificity Protein Phosphatase 3 [NCIt concept]
- Eyes Absent Homolog 1 [NCIt concept]
- Low Molecular Weight Phosphotyrosine Protein Phosphatase [NCIt concept]
- M-Phase Inducer Phosphatase 1 [NCIt concept]
- PTPN11 Gene [NCIt concept]
- PTPN11 wt Allele [NCIt concept]
- Protein-tyrosine phosphatase, nonreceptor-type, 11 [OMIM gene]
- protein tyrosine phosphatase non-receptor type 11 [HGNC gene]
- protein tyrosine phosphatase non-receptor type 11 [ORDO Gene]
Currated CISMeF NLP mapping
- Tyrosine-Protein Phosphatase Non-Receptor Type 11 [NCIt concept]
Indexing information
- 3-(2-(5-(N-(4-fluorobenzyl)sulfamoyl)-2-oxoindolin-3-ylidene)hydrazinyl)benzoic acid methyl ester [MeSH Supplementary Concept]
- HJ24 aptamer [MeSH Supplementary Concept]
- compound 220-324 [MeSH Supplementary Concept]
Record concept(s)
- protein tyrosine phosphatase, Non-Receptor type 11 [MeSH concept]
Related MeSH Supplementary Concept(s)
- PTPN11 protein, human [MeSH Supplementary Concept]
- Ptpn11 protein, mouse [MeSH Supplementary Concept]
- Ptpn11 protein, rat [MeSH Supplementary Concept]
- protein tyrosine phosphatase, non-receptor type 11, a, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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