receptors, leptin

Preferred Label : receptors, leptin;

MeSH definition : Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is mediated through the JAK2/STAT3 pathway to regulate food intake, energy balance and fat storage.;

MeSH synonym : lepr protein; leptin binding protein; receptor, leptin; ob receptor; cd295 antigens; leptin receptor; leptin-binding protein; receptor, ob; antigens, cd295; leptin receptors;

MeSH hyponym : OBRb receptor; OBRa receptor; leptin receptor, small isoform; Receptor, OBRa; Receptor, OBRb; Leptin Receptor, Large Isoform;

Is substance : O;

Details

Origin ID

D054411;

UMLS CUI

C0385463;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
Currated CISMeF NLP mapping
- Leptin Receptor [NCIt concept]
Indexing information
- D-Ser allo-aca peptide [MeSH Supplementary Concept]
- threonyl-glutamyl-norvalyl-alanyl-leucyl-leucyl-seryl-arginyl-aminocaproamide [MeSH Supplementary Concept]
Record concept(s)
- OBRa receptor [MeSH concept]
- OBRb receptor [MeSH concept]
- leptin receptor, small isoform [MeSH concept]
- receptors, leptin [MeSH concept]
Related MeSH Supplementary Concept(s)
- LEPR protein, human [MeSH Supplementary Concept]
- Leprot protein, rat [MeSH Supplementary Concept]
- leptin receptor, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- Leptin Receptor [NCIt concept]

Keyword's position in hierarchy(ies) :

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