transforming growth factor beta2

Preferred Label : transforming growth factor beta2;

MeSH definition : A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.;

MeSH synonym : polyergin; suppressor factor, t-cell, glioblastoma-derived; tgf-beta-2; tgf-beta2; bsc-1 cell growth inhibitor; glioblastoma derived t cell suppressor factor; glioblastoma-derived t-cell suppressor factor; cartilage-inducing factor-b; cartilage inducing factor b; bsc 1 cell growth inhibitor;

CISMeF synonym : TGFB2;

MeSH hyponym : transforming growth factor beta 2 latency associated peptide; TGF-beta2LAP; TGF beta2LAP; TGF-beta2 Latency-Associated Protein; Latency-Associated Protein, TGF-beta2; TGF beta2 Latency Associated Protein;

Is substance : O;

Details

Origin ID

D053781;

UMLS CUI

C0079441;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Transforming Growth Factor Beta-2 [NCIt concept]
- transforming growth factor beta 2 [ORDO Gene]
Record concept(s)
- transforming growth factor beta 2 latency associated peptide [MeSH concept]
- transforming growth factor beta2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- TGFB2 protein, human [MeSH Supplementary Concept]
- Tgfb2 protein, mouse [MeSH Supplementary Concept]
- Tgfb2 protein, rat [MeSH Supplementary Concept]
- spaw protein, zerbafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Transforming Growth Factor Beta-2 [NCIt concept]
- transforming growth factor beta 2 [ORDO Gene]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients